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Molecular Templates, Inc. (MTEM)

NasdaqCM - NasdaqCM Delayed price. Currency in USD
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1.7050+0.1150 (+7.23%)
At close: 04:00PM EDT
1.7000 -0.00 (-0.29%)
After hours: 06:02PM EDT

Insider transactions

Currency in USD
Insider purchases - Last 6 monthsSharesTrans
Purchases00
SalesN/A0
Net shares purchased (sold)00
Total insider shares held212.87kN/A
% net shares purchased (sold)N/AN/A
Net institutional purchases - Prior quarter to latest quarterShares
Net shares purchased (sold)N/A
% change in institutional shares heldN/A

Insider transactions reported - last two years

InsiderTransactionTypeValueDateShares

LALANDE KEVIN M
Director and Beneficial Owner of more than 10% of a Class of Security

Stock Award(Grant) at price 1.90 per share.Indirect332,50002 Apr 2024175,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 0.47 per share.Direct2,000,00017 Jul 20234,255,319

KIM JASON S
President

Conversion of Exercise of derivative security at price 0.71 per share.Direct8,58307 Jul 202212,089

MCLENNAN SEAN
Chief Financial Officer

Purchase at price 0.82 per share.Direct24,47716 Jun 202230,000

LALANDE KEVIN M
Director and Beneficial Owner of more than 10% of a Class of Security

Purchase at price 0.87 - 0.91 per share.Indirect198,38015 Jun 2022222,000

SHV MANAGEMENT SERVICES, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 0.87 - 0.91 per share.Indirect198,38015 Jun 2022222,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 1.17 per share.Indirect234,00016 May 2022200,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Indirect16 May 2022200,000

POMA ERIC E. PH.D.
Chief Executive Officer

Conversion of Exercise of derivative security at price 0.71 per share.Direct24,25127 Apr 202234,156

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 4.04 per share.Indirect807,18006 Jan 2022200,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 4.04 per share.Indirect807,18006 Jan 2022200,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 6.00 per share.Indirect4,500,00021 Sept 2021750,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 6.00 per share.Indirect4,500,00021 Sept 2021750,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 6.13 per share.Indirect613,00016 Sept 2021100,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 6.13 per share.Indirect613,00016 Sept 2021100,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 7.00 - 7.09 per share.Direct1,091,65627 Jul 2021155,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 7.00 - 7.09 per share.Direct1,091,65627 Jul 2021155,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 6.96 - 7.13 per share.Direct1,722,50220 Jul 2021244,382

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 6.96 - 7.13 per share.Direct1,722,50220 Jul 2021244,382

POMA ERIC E. PH.D.
Chief Executive Officer

Conversion of Exercise of derivative security at price 0.71 per share.Direct2,53006 Jul 20213,563

KIM JASON S
President

Sale at price 8.36 per share.Direct23,15728 Jun 20212,770

KIM JASON S
President

Conversion of Exercise of derivative security at price 0.71 per share.Direct22,74728 Jun 202132,038

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.08 per share.Indirect329,94119 Apr 202140,852

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.08 per share.Indirect329,94119 Apr 202140,852

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.62 per share.Indirect1,292,65515 Apr 2021150,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.62 per share.Indirect1,292,65515 Apr 2021150,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 7.81 - 8.37 per share.Indirect2,037,01014 Apr 2021250,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 7.81 - 8.37 per share.Indirect2,037,01014 Apr 2021250,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.02 - 8.23 per share.Indirect2,340,46312 Apr 2021285,664

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.02 - 8.23 per share.Indirect2,340,46312 Apr 2021285,664

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.22 - 8.24 per share.Indirect4,114,82008 Apr 2021500,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.22 - 8.24 per share.Indirect4,114,82008 Apr 2021500,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 9.44 per share.Indirect1,887,10005 Apr 2021200,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 9.44 per share.Indirect1,887,10005 Apr 2021200,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.45 per share.Direct915,84829 Mar 202180,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.45 per share.Direct915,84829 Mar 202180,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.29 - 11.48 per share.Indirect3,513,86624 Feb 2021310,004

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.29 - 11.48 per share.Indirect3,513,86624 Feb 2021310,004

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 12.65 per share.Direct14,999,99018 Feb 20211,185,770

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 12.65 per share.Direct14,999,99018 Feb 20211,185,770

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.69 per share.Indirect935,34401 Feb 202180,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.69 per share.Indirect935,34401 Feb 202180,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.94 per share.Indirect955,00029 Jan 202180,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 11.94 per share.Indirect955,00029 Jan 202180,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.18 - 8.62 per share.Indirect3,727,44110 Dec 2020445,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.18 - 8.62 per share.Indirect3,727,44110 Dec 2020445,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 9.05 - 9.16 per share.Indirect1,456,61610 Nov 2020160,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 9.05 - 9.16 per share.Indirect1,456,61610 Nov 2020160,000

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.33 - 10.86 per share.Indirect4,734,19006 Nov 2020545,335

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.33 - 10.86 per share.Indirect4,734,19006 Nov 2020545,335

BIOTECH TARGET N.V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.83 - 9.40 per share.Indirect1,458,00030 Oct 2020160,000

BIOTECH TARGET N V
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.83 - 9.40 per share.Indirect1,458,00030 Oct 2020160,000

LALANDE KEVIN M
Director and Beneficial Owner of more than 10% of a Class of Security

Sale at price 13.05 per share.Indirect6,525,00016 Sept 2020500,000

SHV MANAGEMENT SERVICES, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Sale at price 13.05 per share.Indirect6,525,00016 Sept 2020500,000

LONGITUDE CAPITAL PARTNERS III, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Sale at price 10.75 per share.Indirect37,56828 Aug 20203,496

LALANDE KEVIN M
Director and Beneficial Owner of more than 10% of a Class of Security

Sale at price 16.51 per share.Indirect4,953,00020 May 2020300,000

SHV MANAGEMENT SERVICES, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Sale at price 16.51 per share.Indirect4,953,00020 May 2020300,000

KIM JASON S
President

Conversion of Exercise of derivative security at price 0.42 per share.Direct22,73703 Jan 202054,136

HIRSCH DAVID
Director and Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.00 per share.Indirect7,496,00025 Nov 2019937,000

HIRSCH DAVID
Director and Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.00 per share.Indirect7,500,00025 Nov 2019937,500

LONGITUDE CAPITAL PARTNERS III, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.00 per share.Indirect7,496,00025 Nov 2019937,000

LONGITUDE CAPITAL PARTNERS III, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 8.00 per share.Indirect7,500,00025 Nov 2019937,500

MORENSTEIN SCOTT D
Director

Purchase at price 8.00 per share.Indirect3,750,00021 Nov 2019468,750

CDK ASSOCIATES, L.L.C.
Unknown

Purchase at price 3.45 per share.Indirect86,25026 Dec 201825,000

POMA ERIC E. PH.D.
Chief Executive Officer

Conversion of Exercise of derivative security at price 0.42 - 0.71 per share.Direct125,97226 Nov 2018239,896

MORENSTEIN SCOTT D
Director

Purchase at price 5.50 per share.Indirect2,999,99725 Sept 2018545,454

HIRSCH DAVID
Director and Beneficial Owner of more than 10% of a Class of Security

Purchase at price 5.50 per share.Indirect2,007,50021 Sept 2018365,000

LONGITUDE CAPITAL PARTNERS III, L.L.C.
Beneficial Owner of more than 10% of a Class of Security

Purchase at price 5.50 per share.Indirect2,007,50021 Sept 2018365,000

FERNANDES JOEL A
Officer

Purchase at price 3.96 per share.Direct14,10628 Sept 20153,562

PARKER GEORGE G.C.
Director

Conversion of Exercise of derivative security at price 1.30 per share.Direct3,25018 Mar 20152,500

JAEGER WILFRED E
Director

Purchase at price 3.75 per share.Direct93,62518 Feb 201525,000

DAVAR NIPUN
Officer

Purchase at price 2.98 per share.Direct8,95513 Oct 20143,000

SELICK HAROLD E
Chief Executive Officer

Conversion of Exercise of derivative security at price 0.00 per share.Direct002 Oct 201420,942

ANDERSON DAVID L
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 20145,511

BAKER GEORGE LEONARD JR.
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 20146,977

YOUNGER WILLIAM H. JR.
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

GAITHER JAMES C
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

WHITE JAMES N
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

SUTTER HILL VENTURES
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Direct001 Oct 2014417,050

SHEEHAN ANDREW T
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

COXE TENCH C
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

BIRD JEFFREY W M.D., PH.D.
Director and Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

SWEET DAVID E
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

SPEISER MICHAEL L
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

DYCKERHOFF STEFAN A
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

PULLARA SAMUEL J III
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 0.00 per share.Indirect001 Oct 2014417,050

ANDERSON DAVID L
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

BAKER GEORGE LEONARD JR.
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

YOUNGER WILLIAM H. JR.
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

GAITHER JAMES C
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

WHITE JAMES N
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

SHEEHAN ANDREW T
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

COXE TENCH C
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

BIRD JEFFREY W M.D., PH.D.
Director and Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

SUTTER HILL ENTREPRENEURS FUND AI L P
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Direct15,87220 Jun 20143,960

SUTTER HILL ENTREPRENEURS FUND Q P L P
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Direct40,19320 Jun 201410,028

SWEET DAVID E
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

SPEISER MICHAEL L
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

DYCKERHOFF STEFAN A
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

PULLARA SAMUEL J III
Beneficial Owner of more than 10% of a Class of Security

Sale at price 4.01 per share.Indirect56,06520 Jun 201413,988

JAEGER WILFRED E
Director

Sale at price 4.86 per share.Indirect467,97216 Jan 201496,356

JAEGER WILFRED E
Director

Sale at price 4.86 - 4.89 per share.Indirect2,069,71815 Jan 2014424,956

JAEGER WILFRED E
Director

Sale at price 4.87 - 4.90 per share.Indirect3,532,32010 Jan 2014723,900

JAEGER WILFRED E
Director

Sale at price 5.52 - 5.54 per share.Indirect1,781,68515 Jul 2013322,000

JAEGER WILFRED E
Director

Sale at price 5.50 - 5.52 per share.Indirect981,46911 Jul 2013178,000

JAEGER WILFRED E
Director

Sale at price 5.48 - 5.56 per share.Indirect1,213,67105 Jul 2013219,667

JAEGER WILFRED E
Director

Sale at price 5.50 per share.Indirect11,00719 Jun 20132,000

JAEGER WILFRED E
Director

Sale at price 5.50 - 5.53 per share.Indirect687,56918 Jun 2013124,733

SELICK HAROLD E
Chief Executive Officer

Conversion of Exercise of derivative security at price 1.86 per share.Direct36,46917 Jun 201319,607

JAEGER WILFRED E
Director

Sale at price 5.47 - 5.50 per share.Indirect841,52610 Jun 2013153,600

ANDERSON DAVID L
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,051,37331 May 2013533,084

ANDERSON DAVID L
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,525,69331 May 2013820,265

BAKER GEORGE LEONARD JR.
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,094,02831 May 2013540,536

BAKER GEORGE LEONARD JR.
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,547,02731 May 2013831,735

GAITHER JAMES C
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,037,84131 May 2013530,720

GAITHER JAMES C
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,518,92831 May 2013816,628

WHITE JAMES N
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect1,577,12831 May 2013275,529

WHITE JAMES N
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,577,13731 May 2013847,923

SUTTER HILL VENTURES
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Direct1,491,62931 May 2013260,592

SUTTER HILL VENTURES
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Direct1,491,63131 May 2013801,952

SHEEHAN ANDREW T
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,037,89931 May 2013530,730

SHEEHAN ANDREW T
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,518,95631 May 2013816,643

COXE TENCH C
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,462,44831 May 2013604,900

COXE TENCH C
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,731,22831 May 2013930,768

SUTTER HILL VENTURES
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Direct1,491,62931 May 2013260,592

SUTTER HILL VENTURES
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Direct1,491,63131 May 2013801,952

BIRD JEFFREY W M.D., PH.D.
Director and Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,127,37631 May 2013546,362

BIRD JEFFREY W M.D., PH.D.
Director and Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,563,70031 May 2013840,699

SWEET DAVID E
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect3,010,75531 May 2013525,988

SWEET DAVID E
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,505,38731 May 2013809,348

SPEISER MICHAEL L
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect1,495,38431 May 2013261,248

SPEISER MICHAEL L
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,495,39031 May 2013803,973

DYCKERHOFF STEFAN A
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect1,491,62931 May 2013260,592

DYCKERHOFF STEFAN A
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,491,63131 May 2013801,952

PULLARA SAMUEL J III
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.72 per share.Indirect2,983,25731 May 2013521,184

PULLARA SAMUEL J III
Beneficial Owner of more than 10% of a Class of Security

Conversion of Exercise of derivative security at price 1.86 per share.Indirect1,491,63131 May 2013801,952

PEARCE TILLMAN E M.D.
Officer

Sale at price 5.63 per share.Direct225,32022 May 201340,000

PEARCE TILLMAN E M.D.
Officer

Conversion of Exercise of derivative security at price 3.46 per share.Direct69,20022 May 201320,000

COXE TENCH C
Beneficial Owner of more than 10% of a Class of Security

Stock Gift at price 0.00 per share.Indirect012 Nov 2012228,310

PARKER GEORGE G.C.
Director

Sale at price 5.65 per share.Direct127,10011 Oct 201222,500

PARKER GEORGE G.C.
Director

Conversion of Exercise of derivative security at price 1.64 - 1.95 per share.Direct40,00011 Oct 201222,500

JAEGER WILFRED E
Director

Conversion of Exercise of derivative security at price 0.79 - 1.95 per share.Direct81,15004 Sept 201255,000

JAEGER WILFRED E
Director

Sale at price 7.98 - 8.02 per share.Indirect6,295,87727 Aug 2012786,400

FERNANDES JOEL A
Officer

Sale at price 8.10 per share.Direct76,95024 Aug 20129,500

JAEGER WILFRED E
Director

Sale at price 7.50 - 7.52 per share.Indirect672,96622 Aug 201289,600

JAEGER WILFRED E
Director

Conversion of Exercise of derivative security at price 1.86 - 2.05 per share.Indirect1,588,04709 Aug 2012811,003

JAEGER WILFRED E
Director

Sale at price 8.01 per share.Indirect1,001,66213 Jul 2012125,000

FRAZIER HEALTHCARE VI L P
Beneficial Owner of more than 10% of a Class of Security

Sale at price 5.01 - 5.38 per share.Indirect69,965,58521 Feb 201213,737,240

FRAZIER HEALTHCARE VI L P
Beneficial Owner of more than 10% of a Class of Security

Sale at price 3.02 per share.Indirect1,812,00007 Feb 2012600,000

SELICK HAROLD E
Chief Executive Officer

Stock Gift at price 0.00 per share.Direct009 Aug 201136,000