Sarepta Therapeutics’ (SRPT) Exondys 51 uses exon-skipping technology to skip exon 51 of the DMD gene. The drug is designed to bind to exon 51, which leads to an exclusion or skipping of this exon during mRNA processing. Golodirsen uses exon-skipping technology to skip exon 53 of the DMD gene.
Sabrina Carpenter went braless wearing the Mirror Palais Anemone Dress in butter featuring illusion tulle adorned with lace appliqués along the neckline and hem
The arrival of the US M1A1 Abrams tanks in Ukraine was hailed as a turning point in the war. Coming in at roughly $10 million a unit, the Nato stalwart was supposed to provide the armoured fist that would punch through the Russian lines. But tactics evolve quickly in warfare, and Russia’s use of surveillance and hunter-killer drones has led to heavy casualties for Ukraine’s tank fleets. This is alarming for NATO. If Russia has found critical vulnerabilities in our armour, our borders are beginni
Secretary of State Antony Blinken’s multi-day trip to China this week caps a particularly busy stretch of meetings between US and Chinese officials. Treasury Secretary Janet Yellen was in Beijing earlier this month where she delivered remarks about establishing a floor underneath the US-China relationship and was photographed drinking a beer at a local brewery. On April 5, US and Chinese defence officials held maritime talks for the first time in three years. And on April 16, US Defense Secretar
Anastasia Ivleeva fell foul of a law that sanctions remarks discrediting the Russian military.
A dog walker made the horrific discovery on Tuesday morning
The striker was again guilty of a huge miss as Everton all but ended Liverpool’s title hopes
The casino, which would only be the second in Malaysia, could revive the struggling property.
A Secret Service agent assigned to Vice President Kamala Harris’ detail was removed from their assignment after displaying behavior that colleagues found “distressing,” the agency said.
A royal expert says Prince Harry is in a painful place after writing about Kate Middleton in his bombshell-filled memoir, 'Spare.'
In the aftermath of a particularly demoralising defeat, former Liverpool manager Gerard Houllier once appealed to the Kop with the observation: “We don’t destroy our heroes today when we worshipped them yesterday.”
Erik ten Hag has told Marcus Rashford he must take his share of the blame for Manchester United’s struggles despite offering the striker his full backing in the face of “months of abuse”.
The "chosen ones" are reportedly sad they didn't get new roles after Prince William and Kate Middleton's latest appointments.
The Taiwanese host is back in Penang again after filming in the island back in 2015 and 2019
The Hong Kong actress is said to star in a drama by "The Queen of News" producer
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Secretary of state met Xi Jinping in Beijing and warned of sanctions over China’s support for Russian arms industry
STORY: Nineteen-year-old Kkavya landed in Bengaluru with dreams of getting a degree in English literature and an exciting job at a tech firm.During a job interview, Khavya, who hails from Kashmir, was told she would have amazing job opportunities in India's Silicon Valley.She was sold the "Bengaluru dream.""What was promised to me when I came to work, they were like, 'Listen, the weather is going to be amazing, you're going to get paid, come work for us for seven hours, go home, take a beer, chill, sleep."After three years in the city, the dream is falling apart, and fast.One problem is the traffic."Do you see the horn? Did you hear it? This is my nightmare."As it was transformed into India's tech hub, the city has struggled to keep up with the massive population influx.Kkavya now spends up to five or six hours on her daily commutes.In the 1990s, Bengaluru rapidly became India's answer to Silicon Valley.It attracted millions of workers and the regional headquarters of some of the world's biggest IT companies.But unrestrained urban expansion has affected Bengaluru's character as a liveable city.With the city poised to vote in the second phase of India's national election on Friday (April 26), Kkavya said she felt frustrated to see that these issues are rarely addressed by local politicians and candidates."We are that sad now, we don't even think that this is something politicians can fix, because they never talk about it. Traffic is our problem, roads are our problem, hospital is your problem. So when I tell my boss that I can't reach on time, it's my problem, not the people who made the roads, not the people who are responsible for the traffic."And she struggles every morning to get water for her daily use. Weak southwest monsoon rains last year failed to replenish depleted groundwater causing shortages.This forced residents to ration water use and pay a much higher price.Water rates at her apartment have gone up by almost four times from about $8.40 per month to more than $27. "Water is expensive as it gets. It is something like we fight for, cause I remember, two days back, this building and the next building had a war over one tank. Because there was only one tank available, and we both wanted it, so basically they paid more and they got it."
Yahya Sinwar, the Hamas leader, is blocking a deal to release Israeli hostages, the Biden administration has said.
A young student started choking on a piece of candy during recess at a school in Bangkok, Thailand, in January of this year. CCTV footage captures the panic as classmates rush to her aid, prompting a teacher to quickly perform the Heimlich maneuver, ultimately saving the child.
For the past few years, the US economy has been growing at a pace that seemed too good to be true.
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