Alcoa and Facebook are big market movers

NEW YORK (AP) -- Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:

NYSE

Alcoa Inc., up 47 cents to $13

Industry analysts raise their price targets for the aluminum maker's stock after the company weathered a rough patch in the recent quarter.

Harman International Industries Inc., up $1.81 cents to $107.26

After a sharp sell-off of its shares, Raymond James upgraded the lighting and audio company.

Constellation Brands Inc., down 84 cents to $80.64

The beverage seller posted big fourth-quarter profits, fueled by its recent acquisition of Corona beer.

General Motors Co., down 91 cents to $33.62

Morgan Stanley downgraded the Detroit automaker and the sector comes under pressure after another recall, this time from Toyota.

Nasdaq

Facebook Inc., up $4.22 to $62.41

The social network's stock had its second-largest jump of the year after Sheryl Sandberg again insisted that she is staying with the company.

Intuitive Surgical Inc., down $33.20 to $456.64

The medical company warned that its quarterly revenue would be weak, citing less revenue from its da Vinci robotics division.

E-Trade Financial Corp., up $1.20 to $21.18

Bank of America upgraded the online trading platform after a bruising week due to questions about new regulations for markets.

Zogenix Inc., up 22 cents to $2.81

A second day of gains for the pharmaceutical company, which won regulatory approval to sell its controversial prescription painkiller Zohydro.