BiomX Inc. (NYSE American : PHGE), a clinical stage company developing natural and engineered phage therapies that target specific pathogenic bacteria, today presented preclinical data from its phage panel for the treatment of inflammatory bowel disease at the Infectious Disease Society of America (IDSA) Infectious Disease Week (IDWeek) 2020 conference. The poster presentation details a phage therapy panel, comprised of phage directed against Klebsiella pneumoniae, showing a broad target host range and the potential to address carbapenem-resistant and extended spectrum beta-lactamase (ESBL)-producing bacteria.
Acute infections caused by resistant Klebsiella bacteria are recognized as a public health concern by various national and international authorities and organizations, including those providing grant-based funding for novel approaches to treatment. The World Health Organization classifies carbapenem-resistant and ESBL-producing Enterobacteriaceae, which include Klebsiella pneumoniae, as a critical threat, the highest threat level.
Abstract Title: Activity of bacteriophage against multidrug resistant Klebsiella pneumoniae (Poster #1564)
Session: Treatment of Antimicrobial Resistant Infections
Lead Author: Sailaja Puttagunta, M.D., CMO of BiomX
The abstract can be found on the IDSA IDWeek website and the poster will be made available on the company’s website once the virtual program begins on Oct. 21, 2020, at 7 a.m. EDT at https://www.biomx.com/publications-2/.
BiomX is a clinical-stage biotechnology company developing both natural and engineered phage cocktails designed to target and destroy bacteria that affect the appearance of skin, as well as harmful bacteria in chronic diseases, such as inflammatory bowel disease (IBD), primary sclerosing cholangitis (PSC), and colorectal cancer (CRC). BiomX discovers and validates proprietary bacterial targets and customizes phage compositions against these targets.
Additional information is available at www.biomx.com.
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Noel Kurdi, BiomX
VP Investor Relations and Strategy
Rich Allan, Solebury Trout