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Here's Why Wave Life Sciences Crashed Today

Here's Why Wave Life Sciences Crashed Today

Shares of Wave Life Sciences (NASDAQ: WVE) are down 29% at 1:29 p.m. EDT after the company announced that WVE-120102 and WVE-120101, two of its drugs to treat Huntington's disease, failed to show an effect in early stage clinical trials. Huntington's disease is caused by different mutations in the huntingtin protein. WVE-120101 and WVE-120102 are designed to reduce the expression of mutant huntingtin protein (mHTT) for patients with the SNP1 and SNP2 mutations, respectively.