| Top Institutional Holders |
|---|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Wellington Management Company, LLP | 6,313,066 | 9.68 | 295,577,750 | Mar 31, 2013 | | Price (T.Rowe) Associates Inc | 4,368,900 | 6.70 | 204,551,898 | Mar 31, 2013 | | Vanguard Group, Inc. (The) | 4,265,535 | 6.54 | 199,712,348 | Mar 31, 2013 | | BlackRock Fund Advisors | 3,777,197 | 5.79 | 176,848,363 | Mar 31, 2013 | | Bank of New York Mellon Corporation | 3,573,989 | 5.48 | 167,334,164 | Mar 31, 2013 | | Federated Investors, Inc. | 2,587,516 | 3.97 | 121,147,499 | Mar 31, 2013 | | Putnam Investment Management, LLC | 2,265,907 | 3.47 | 106,089,765 | Mar 31, 2013 | | State Street Corporation | 1,847,110 | 2.83 | 86,481,690 | Mar 31, 2013 | | Wells Fargo & Company | 1,813,853 | 2.78 | 84,924,597 | Mar 31, 2013 | | BlackRock Institutional Trust Company, N.A. | 1,775,292 | 2.72 | 83,119,171 | Mar 31, 2013 |
|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Federated Kaufmann Fund | 2,020,000 | 3.10 | 86,940,800 | Jan 31, 2013 | | Vanguard Specialized-Health Care Fund | 1,323,142 | 2.03 | 56,948,031 | Jan 31, 2013 | | iShares Core S&P Smallcap ETF | 1,106,826 | 1.70 | 51,821,593 | Mar 31, 2013 | | Vanguard Small-Cap Index Fund | 1,060,990 | 1.63 | 44,614,629 | Dec 31, 2012 | | Price (T.Rowe) Health Sciences Fund | 1,025,000 | 1.57 | 47,990,500 | Mar 31, 2013 | | iShares Russell 2000 Index Fund | 1,014,628 | 1.56 | 47,504,882 | Mar 31, 2013 | | Price (T.Rowe) Mid Cap Growth Fund | 1,000,000 | 1.53 | 46,820,000 | Mar 31, 2013 | | Vanguard Total Stock Market Index Fund | 850,670 | 1.30 | 35,770,673 | Dec 31, 2012 | | Fidelity Select Portfolios - Biotechnology | 830,908 | 1.27 | 38,903,112 | Mar 31, 2013 | | Price (T.Rowe) Small Cap Stock Fund | 828,400 | 1.27 | 38,785,688 | Mar 31, 2013 |
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View Transactions for Insiders & Institutional Holders Value shown is computed using the security's price on the report date given. Currency in USD. |