| INSIDER & RULE 144 TRANSACTIONS REPORTED - LAST TWO YEARS |
| Date | Insider | Shares | Transaction | Value* | | 13-Jan-10 | SHAPIRO DEVRA G Officer | 5,000 | Option Exercise at $1.60 per share. | $8,000 | | 13-Jan-10 | SHAPIRO DEVRA G Officer | 5,000 | Automatic Sale at $34.55 per share. | $172,750 | | 6-Jan-10 | SINGER ADAM D MD Officer | 4,000 | Automatic Sale at $35.03 per share. | $140,120 | | 5-Jan-10 | RUSSELL RICHARD G Officer | 5,000 | Automatic Sale at $35.08 per share. | $175,400 | | 4-Jan-10 | RUSSELL RICHARD G Officer | 1,290 | Automatic Sale at $34.10 per share. | $43,989 | | 31-Dec-09 | TAYLOR R JEFFREY Officer | 722 | Acquisition (Non Open Market) at $13.85 per share. | $9,999 | | 31-Dec-09 | RUSSELL RICHARD G Officer | 722 | Acquisition (Non Open Market) at $13.85 per share. | $9,999 | | 18-Dec-09 | TAYLOR R JEFFREY Officer | 5,000 | Option Exercise at $1.60 per share. | $8,000 | | 18-Dec-09 | TAYLOR R JEFFREY Officer | 5,000 | Sale at $30.48 per share. | $152,400 | | 18-Dec-09 | TIMPE CHUCK Director | 24,194 | Sale at $30.92 per share. | $748,078 | | 17-Dec-09 | SARRIA FERNANDO Officer | 846 | Sale at $30.76 per share. | $26,022 | | 15-Dec-09 | SARRIA FERNANDO Officer | 100 | Sale at $31.50 per share. | $3,150 | | 14-Dec-09 | SARRIA FERNANDO Officer | 114 | Sale at $31.50 per share. | $3,591 | | 4-Dec-09 | SARRIA FERNANDO Officer | 2,873 | Option Exercise at $0.77 - $1.6 per share. | N/A | | 4-Dec-09 | SARRIA FERNANDO Officer | 3,313 | Sale at $33 per share. | $109,329 | | 3-Dec-09 | SARRIA FERNANDO Officer | 822 | Option Exercise at $0.77 per share. | $632 | | 3-Dec-09 | SARRIA FERNANDO Officer | 822 | Sale at $33 per share. | $27,126 | | 2-Dec-09 | SARRIA FERNANDO Officer | 162 | Option Exercise at $1.60 per share. | $259 | | 2-Dec-09 | SARRIA FERNANDO Officer | 162 | Sale at $33 per share. | $5,346 | | 1-Dec-09 | SINGER ADAM D MD Officer | 4,000 | Automatic Sale at $31.89 per share. | $127,560 | | 25-Nov-09 | SARRIA FERNANDO Officer | 2,862 | Option Exercise at $0.77 - $1.6 per share. | N/A | | 25-Nov-09 | SARRIA FERNANDO Officer | 5,581 | Sale at $33 per share. | $184,173 | | 5-Nov-09 | SINGER ADAM D MD Officer | 10,101 | Sale at $32 per share. | $323,232 | | 4-Nov-09 | COOPER THOMAS P Director | 3,000 | Option Exercise at $5.25 per share. | $15,750 | | 4-Nov-09 | COOPER THOMAS P Director | 3,000 | Sale at $31.80 per share. | $95,400 | | 3-Nov-09 | SINGER ADAM D MD Officer | 3,000 | Automatic Sale at $31.70 per share. | $95,100 | | 20-Oct-09 | RUSSELL RICHARD G Officer | 66 | Automatic Sale at $34 per share. | $2,244 | | 19-Oct-09 | RUSSELL RICHARD G Officer | 3,644 | Automatic Sale at $34 per share. | $123,896 | | 6-Oct-09 | SINGER ADAM D MD Officer | 3,000 | Automatic Sale at $32.35 per share. | $97,050 | | 10-Sep-09 | TIMPE CHUCK Director | 1,000 | Sale at $30 per share. | $30,000 | | 10-Sep-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $30 per share. | $30,000 | | 1-Sep-09 | SINGER ADAM D MD Officer | 2,000 | Automatic Sale at $28.87 per share. | $57,740 | | 13-Aug-09 | RUSSELL RICHARD G Officer | 5,000 | Automatic Sale at $32 per share. | $160,000 | | 12-Aug-09 | RUSSELL RICHARD G Officer | 5,000 | Automatic Sale at $31.05 per share. | $155,250 | | 11-Aug-09 | RUSSELL RICHARD G Officer | 5,000 | Automatic Sale at $30 per share. | $150,000 | | 10-Aug-09 | TAYLOR R JEFFREY Officer | 15,000 | Sale at $30.01 per share. | $450,150 | | 7-Aug-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $30 per share. | $30,000 | | 4-Aug-09 | SINGER ADAM D MD Officer | 2,000 | Automatic Sale at $27.19 per share. | $54,380 | | 7-Jul-09 | SINGER ADAM D MD Officer | 2,000 | Automatic Sale at $27.19 per share. | $54,380 | | 23-Jun-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $25.90 - $26.43 per share. | $26,0002 | | 17-Jun-09 | TIMPE CHUCK Director | 2,500 | Sale at $25 per share. | $62,500 | | 2-Jun-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $24.53 - $25.31 per share. | $25,0002 | | 29-May-09 | SINGER ADAM D MD Officer | 300 | Automatic Sale at $25.48 - $25.49 per share. | $7,6452 | | 29-May-09 | RUSSELL RICHARD G Officer | 4,498 | Automatic Sale at $25.27 - $26 per share. | $115,0002 | | 29-May-09 | SHAPIRO DEVRA G Officer | 6,017 | Automatic Sale at $25.27 per share. | $152,049 | | 26-May-09 | SINGER ADAM D MD Officer | 700 | Automatic Sale at $25 - $25.02 per share. | $18,0002 | | 26-May-09 | RUSSELL RICHARD G Officer | 5,502 | Automatic Sale at $24 - $25.01 per share. | $135,0002 | | 26-May-09 | SHAPIRO DEVRA G Officer | 3,983 | Automatic Sale at $25 - $25.02 per share. | $100,0002 | | 26-May-09 | RUSSELL RICHARD G Officer | 400 | Automatic Sale at $25.31 per share. | $10,124 | | 11-May-09 | SINGER ADAM D MD Officer | 2,600 | Sale at $23.46 - $23.61 per share. | $61,0002 | | 11-May-09 | SINGER ADAM D MD Officer | 32,400 | Sale at $23.25 - $23.45 per share. | $757,0002 | | 8-May-09 | RUSSELL RICHARD G Officer | 3,041 | Automatic Sale at $23 - $23.32 per share. | $70,0002 | | 7-May-09 | RUSSELL RICHARD G Officer | 1,959 | Automatic Sale at $23 - $23.4 per share. | $45,0002 | | 7-May-09 | COOPER THOMAS P Director | 9,550 | Option Exercise at $5.25 per share. | $50,137 | | 7-May-09 | COOPER THOMAS P Director | 6,089 | Sale at $22.42 - $22.55 per share. | $137,0002 | | 5-May-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $19.21 - $21.3 per share. | $20,0002 | | 5-May-09 | RUSSELL RICHARD G Officer | 4,700 | Automatic Sale at $20.03 - $20.34 per share. | $95,0002 | | 5-May-09 | SHAPIRO DEVRA G Officer | 21,001 | Automatic Sale at $20 - $21.45 per share. | $435,0002 | | 7-Apr-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $17.41 - $17.82 per share. | $18,0002 | | 20-Mar-09 | RUSSELL RICHARD G Officer | 300 | Automatic Sale at $20.08 - $20.16 per share. | $6,0352 | | 20-Mar-09 | SHAPIRO DEVRA G Officer | 8,999 | Automatic Sale at $20 - $20.22 per share. | $181,0002 | | 19-Mar-09 | RUSSELL RICHARD G Officer | 5,000 | Automatic Sale at $19.09 - $19.38 per share. | $96,0002 | | 3-Mar-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $15.30 - $15.64 per share. | $15,0002 | | 3-Feb-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $18.40 - $18.61 per share. | $19,0002 | | 6-Jan-09 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $15.14 per share. | $15,140 | | 31-Dec-08 | TAYLOR R JEFFREY Officer | 308 | Acquisition (Non Open Market) at $14.31 per share. | $4,407 | | 31-Dec-08 | RUSSELL RICHARD G Officer | 308 | Acquisition (Non Open Market) at $14.31 per share. | $4,407 | | 26-Dec-08 | RUSSELL RICHARD G Officer | 3,000 | Option Exercise at $1.60 - $5.25 per share. | N/A | | 2-Dec-08 | SINGER ADAM D MD Officer | 1,000 | Automatic Sale at $17.88 per share. | $17,880 | | 17-Nov-08 | RUSSELL RICHARD G Officer | 2,541 | Option Exercise at $1.60 per share. | $4,065 | | 8-Oct-08 | TAYLOR R JEFFREY Officer | 2,000 | Option Exercise at $1.60 per share. | $3,200 | | 26-Aug-08 | BANK OF AMERICA CORP /DE/ Director | 444 | Disposition (Non Open Market) at $0 per share. | N/A | | 26-Aug-08 | BANK OF AMERICA CORP /DE/ Director | 444 | Acquisition (Non Open Market) at $24.57 per share. | $10,909 | | 19-Aug-08 | BANK OF AMERICA CORP /DE/ Director | 444 | Sale at $23.59 per share. | $10,473 | | 21-Jul-08 | SINGER ADAM D MD Officer | 13,000 | Sale at $17.48 per share. | $227,240 | | 21-Jul-08 | SINGER ADAM D MD Officer | 36,000 | Sale at $17.48 per share. | $629,280 | | 21-Jul-08 | MORGENTHALER PARTNERS VII LP Beneficial Owner (10% or more) | 220,838 | Sale at $17.48 per share. | $3,860,248 | | 21-Jul-08 | MORGENTHALER VENTURE PARTNERS IV Beneficial Owner (10% or more) | 494,305 | Sale at $17.48 per share. | $8,640,451 | | 21-Jul-08 | BANK OF AMERICA CORP /DE/ Beneficial Owner (10% or more) | 880,398 | Sale at $17.48 per share. | $15,389,357 | | 6-Jun-08 | SMITH BARRY M Director | 2,734 | Option Exercise at $2.43 - $16 per share. | N/A | | 6-Jun-08 | SMITH BARRY M Director | 1,427 | Disposition (Non Open Market) at $23.20 per share. | $33,106 | | 19-Mar-08 | SINGER ADAM D MD Officer | 345,601 | Acquisition (Non Open Market) at $0 per share. | N/A | | 19-Mar-08 | SINGER ADAM D MD Officer | 345,601 | Disposition (Non Open Market) at $0 per share. | N/A | | 30-Jan-08 | SINGER ADAM D MD Officer | 275,750 | Disposition (Non Open Market) at $0 per share. | N/A | | 30-Jan-08 | MORGENTHALER PARTNERS VII LP Beneficial Owner (10% or more) | 230,790 | Sale at $14.88 per share. | $3,434,155 | | 30-Jan-08 | MORGENTHALER PARTNERS VII LP Beneficial Owner (10% or more) | 840,736 | Acquisition (Non Open Market) | N/A | | 30-Jan-08 | BANK OF AMERICA VENTURES Beneficial Owner (10% or more) | 897,898 | Sale at $14.88 per share. | $13,360,722 | | 30-Jan-08 | BANK OF AMERICA VENTURES Beneficial Owner (10% or more) | 3,329,513 | Acquisition (Non Open Market) | N/A | | 30-Jan-08 | CB HEALTHCARE FUND LP Beneficial Owner (10% or more) | 420,237 | Sale at $14.88 per share. | $6,253,126 | | 30-Jan-08 | CB HEALTHCARE FUND LP Beneficial Owner (10% or more) | 1,568,783 | Acquisition (Non Open Market) | N/A | | 30-Jan-08 | BESSEMER VENTURE PARTNERS IV LP Beneficial Owner (10% or more) | 491,943 | Sale at $14.88 per share. | $7,320,111 | | 30-Jan-08 | BESSEMER VENTURE PARTNERS IV LP Beneficial Owner (10% or more) | 1,854,906 | Acquisition (Non Open Market) | N/A | | 30-Jan-08 | MORGENTHALER VENTURE PARTNERS IV Beneficial Owner (10% or more) | 488,370 | Sale at $14.88 per share. | $7,266,945 | | 30-Jan-08 | MORGENTHALER VENTURE PARTNERS IV Beneficial Owner (10% or more) | 1,853,618 | Acquisition (Non Open Market) | N/A | | 24-Jan-08 | SINGER ADAM D MD Officer | 345,601 | Statement of Ownership | N/A | | 24-Jan-08 | SINGER ADAM D MD Officer | 275,750 | Statement of Ownership | N/A | | 24-Jan-08 | TAYLOR R JEFFREY Officer | 156,250 | Statement of Ownership | N/A | | 24-Jan-08 | SARRIA FERNANDO Officer | 4,219 | Statement of Ownership | N/A | | 24-Jan-08 | RUSSELL RICHARD G Officer | 60,430 | Statement of Ownership | N/A | | 24-Jan-08 | SHAPIRO DEVRA G Officer | 138,512 | Statement of Ownership | N/A | | 24-Jan-08 | SMITH TOM Director | 23,535 | Statement of Ownership | N/A | | 24-Jan-08 | TIMPE CHUCK Director | 27,694 | Statement of Ownership | N/A | | 24-Jan-08 | SMITH BARRY M Director | 27,345 | Statement of Ownership | N/A |
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* = Where indicated, some values are estimates. 1 = Potential proceeds estimated by the filer. 2 = Estimated based on the average of multiple prices reported. 3 = Multiple dates reported. Most recent date shown. |
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